AI Vs. Drug Resistance
Drug resistance is a major factor limiting the effect of therapies designed to cure cancers and other complex diseases. Francesca Buffa manages a ERC Consolidator Grant aimed at developing computational methods that allow us to better understand drug resistance. Her methods merge network analysis, agent-based modeling, and genomics. The cell is considered as a network of genes and its behavior is modeled as the result of the interactions (signaling activity) of many genes. In turn, cell interactions with each other determine the growth of cancer.